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Sanmartin Berglund, Johan, ProfessorORCID iD iconorcid.org/0000-0003-4312-2246
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Publications (10 of 83) Show all publications
Anderberg, P., Eivazzadeh, S. & Sanmartin Berglund, J. (2019). A Novel Instrument for Measuring Older People's Attitudes Toward Technology (TechPH): Development and Validation. Journal of Medical Internet Research, 21(5), Article ID e13951.
Open this publication in new window or tab >>A Novel Instrument for Measuring Older People's Attitudes Toward Technology (TechPH): Development and Validation
2019 (English)In: Journal of Medical Internet Research, ISSN 1438-8871, E-ISSN 1438-8871, Vol. 21, no 5, article id e13951Article in journal (Refereed) Published
Abstract [en]

Background: The use of health technology by older people is coming increasingly in focus with the demographic changes. Health information technology is generally perceived as an important factor in enabling increased quality of life and reducing the cost of care for this group. Age-appropriate design and facilitation of technology adoption are important to ensure functionality and removal of various barriers to usage. Development of assessment tools and instruments for evaluating older persons' technology adoption and usage as well as measuring the effects of the interventions are of high priority. Both usability and acceptance of a specific technology or service are important factors in evaluating the impact of a health information technology intervention. Psychometric measures are seldom included in evaluations of health technology. However, basic attitudes and sentiments toward technology (eg, technophilia) could be argued to influence both the level of satisfaction with the technology itself as well as the perception of the health intervention outcome. Objective: The purpose of this study is to develop a reduced and refined instrument for measuring older people's attitudes and enthusiasm for technology based on relevant existing instruments for measuring technophilia A requirement of the new instrument is that it should be short and simple to make it usable for evaluation of health technology for older people. Methods: Initial items for the TechPH questionnaire were drawn from a content analysis of relevant existing technophilia measure instruments. An exploratory factor analysis was conducted in a random selection of persons aged 65 years or older (N=374) on eight initial items. The scale was reduced to six items, and the internal consistency and reliability of the scale were examined. Further validation was made by a confirmatory factor analysis (CFA). Results: The exploratory factor analysis resulted in two factors. These factors were analyzed and labeled techEnthusiasm and techAnxiety. They demonstrated relatively good internal consistency (Cronbach alpha=.72 and .68, respectively). The factors were confirmed in the CFA and showed good model fit (chi(2)(8)=21.2, chi(2)/df=2.65, comparative fit index=0.97, adjusted goodness-of-fit index=0.95, root mean square error of approximation=0.067, standardized root mean square residual=0.036). Conclusions: The construed TechPH score showed expected relations to external real-world criteria, and the two factors showed interesting internal relations. Different technophilia personality traits distinguish clusters with different behaviors of adaptation as well as usage of new technology. Whether there is an independent association with the TechPH score against outcomes in health technology projects needs to be shown in further studies. The instrument must also be validated in different contexts, such as other countries.

Place, publisher, year, edition, pages
JMIR PUBLICATIONS, INC, 2019
Keywords
technophilia, aging, internet, health technology, eHealth
National Category
Nursing Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:bth-18031 (URN)10.2196/13951 (DOI)000469099700001 ()31124467 (PubMedID)
Note

open access

Available from: 2019-06-14 Created: 2019-06-14 Last updated: 2019-06-20Bibliographically approved
López-Fauqued, M., Campora, L., Delannois, F., El Idrissi, M., Oostvogels, L., De Looze, F. J., . . . Sanmartin Berglund, J. (2019). Safety profile of the adjuvanted recombinant zoster vaccine: Pooled analysis of two large randomised phase 3 trials. Vaccine, 37(18), 2482-2493
Open this publication in new window or tab >>Safety profile of the adjuvanted recombinant zoster vaccine: Pooled analysis of two large randomised phase 3 trials
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2019 (English)In: Vaccine, ISSN 0264-410X, E-ISSN 1873-2518, Vol. 37, no 18, p. 2482-2493Article in journal (Refereed) Published
Abstract [en]

Background: The ZOE-50 (NCT01165177) and ZOE-70 (NCT01165229) phase 3 clinical trials showed that the adjuvanted recombinant zoster vaccine (RZV) was ≥90% efficacious in preventing herpes zoster in adults. Here we present a comprehensive overview of the safety data from these studies. Methods: Adults aged ≥50 (ZOE-50) and ≥70 (ZOE-70) years were randomly vaccinated with RZV or placebo. Safety analyses were performed on the pooled total vaccinated cohort, consisting of participants receiving at least one dose of RZV or placebo. Solicited and unsolicited adverse events (AEs) were collected for 7 and 30 days after each vaccination, respectively. Serious AEs (SAEs) were collected from the first vaccination until 12 months post-last dose. Fatal AEs, vaccination-related SAEs, and potential immune-mediated diseases (pIMDs) were collected during the entire study period. Results: Safety was evaluated in 14,645 RZV and 14,660 placebo recipients. More RZV than placebo recipients reported unsolicited AEs (50.5% versus 32.0%); the difference was driven by transient injection site and solicited systemic reactions that were generally seen in the first week post-vaccination. The occurrence of overall SAEs (RZV: 10.1%; Placebo: 10.4%), fatal AEs (RZV: 4.3%; Placebo: 4.6%), and pIMDs (RZV: 1.2%; Placebo: 1.4%) was balanced between groups. The occurrence of possible exacerbations of pIMDs was rare and similar between groups. Overall, except for the expected local and systemic symptoms, the safety results were comparable between the RZV and Placebo groups irrespective of participant age, gender, or race. Conclusions: No safety concerns arose, supporting the favorable benefit-risk profile of RZV. © 2019 GlaxoSmithKline Biologicals SA

Place, publisher, year, edition, pages
Elsevier Ltd, 2019
Keywords
Reactogenicity, Safety, Vaccine, Varicella-zoster virus, placebo, varicella zoster vaccine, acute kidney failure, adult, age distribution, aged, alopecia areata, aortic stenosis, arthralgia, Article, atrial fibrillation, autoimmune pancreatitis, autoimmune thyroiditis, backache, brain infarction, cardiogenic shock, cardiopulmonary insufficiency, celiac disease, cerebrovascular accident, chill, chronic gastritis, chronic obstructive lung disease, clinical evaluation, cohort analysis, controlled study, coughing, Crohn disease, disease course, dizziness, drug efficacy, drug safety, erythema nodosum, facial nerve paralysis, fatigue, female, fever, fibrosing alveolitis, follow up, glomerulonephritis, Graves disease, Guillain Barre syndrome, headache, heart atrium flutter, heart failure, heart infarction, herpes zoster, human, idiopathic thrombocytopenic purpura, immunoglobulin A nephropathy, information processing, injection site erythema, injection site pain, injection site pruritus, injection site swelling, injection site warmth, insulin dependent diabetes mellitus, lichen planus, lung fibrosis, lung tumor, major clinical study, malaise, male, mixed connective tissue disease, multiple organ failure, multiple sclerosis, myalgia, neuritis, oropharynx pain, pancreas carcinoma, paraneoplastic neuropathy, pemphigus, phase 3 clinical trial, pneumonia, polyradiculoneuropathy, population research, priority journal, psoriasis, psoriatic arthritis, race, radiculitis, randomized controlled trial, Raynaud phenomenon, respiratory failure, retina detachment, rheumatic polymyalgia, rheumatoid arthritis, rhinopharyngitis, sepsis, septic shock, sex ratio, single blind procedure, spondyloarthropathy, supraventricular tachycardia, syndrome CREST, systemic juvenile idiopathic arthritis, systemic lupus erythematosus, tachycardia, temporal arteritis, trigeminal nerve disease, trigeminus neuralgia, ulcerative colitis, upper respiratory tract infection, uveitis, vaccination, vitiligo
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:bth-17834 (URN)10.1016/j.vaccine.2019.03.043 (DOI)000466622500009 ()2-s2.0-85063476515 (Scopus ID)
Note

open access

Available from: 2019-04-18 Created: 2019-04-18 Last updated: 2019-06-14Bibliographically approved
Olsson, A., Alfredsson, J., Ramstrom, S., Svedjeholm, R., Kenny, D., Hakansson, E., . . . Berg, S. (2018). Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer's chase technique: a randomized pilot study. Perfusion, 33(3), 185-193
Open this publication in new window or tab >>Better platelet function, less fibrinolysis and less hemolysis in re-transfused residual pump blood with the Ringer's chase technique: a randomized pilot study
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2018 (English)In: Perfusion, ISSN 0267-6591, E-ISSN 1477-111X, Vol. 33, no 3, p. 185-193Article in journal (Refereed) Published
Abstract [en]

Introduction: Residual pump blood from the cardiopulmonary bypass (CPB) circuit is often collected into an infusion bag (IB) and re-transfused. An alternative is to chase the residual blood into the circulation through the arterial cannula with Ringer's acetate. Our aim was to assess possible differences in hemostatic blood quality between these two techniques. Methods: Forty adult patients undergoing elective coronary artery bypass graft surgery with CPB were randomized to receive the residual pump blood by either an IB or through the Ringer's chase (RC) technique. Platelet activation and function (impedance aggregometry), coagulation and hemolysis variables were assessed in the re-transfused blood and in the patients before, during and after surgery. Results are presented as median (25-75 quartiles). Results: Total hemoglobin and platelet levels in the re-transfused blood were comparable with the two methods, as were soluble platelet activation markers P-selectin and soluble glycoprotein VI (GPVI). Platelet aggregation (U) in the IB blood was significantly lower compared to the RC blood, with the agonists adenosine diphosphate (ADP) 24 (10-32) vs 46 (33-65), p<0.01, thrombin receptor activating peptide (TRAP) 50 (29-73) vs 69 (51-92), p=0.04 and collagen 24 (17-28) vs 34 (26-59), p<0.01. The IB blood had higher amounts of free hemoglobin (mg/L) (1086 (891-1717) vs 591(517-646), p<0.01) and D-dimer 0.60 (0.33-0.98) vs 0.3 (0.3-0.48), p<0.01. Other coagulation variables showed no difference between the groups. Conclusions: The handling of blood after CPB increases hemolysis, impairs platelet function and activates coagulation and fibrinolysis. The RC technique preserved the blood better than the commonly used IB technique.

Place, publisher, year, edition, pages
SAGE PUBLICATIONS LTD, 2018
Keywords
cardiopulmonary bypass, methods, hemostasis, platelet function tests
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:bth-16119 (URN)10.1177/0267659117733891 (DOI)000429907500003 ()28950757 (PubMedID)
Available from: 2018-04-26 Created: 2018-04-26 Last updated: 2018-04-26Bibliographically approved
Frögren, J., Quitana, M., Anderberg, P. & Sanmartin Berglund, J. (2018). Designing a model app for older persons with cognitive impairment: insights from a usability perspective. Gerontechnology, 17, 80
Open this publication in new window or tab >>Designing a model app for older persons with cognitive impairment: insights from a usability perspective
2018 (English)In: Gerontechnology, ISSN 1569-1101, E-ISSN 1569-111X, Vol. 17, p. 80-Article in journal (Refereed) Published
Abstract [en]

Purpose Research indicates that health-oriented applications on mobile units such as smartphones and PDAs, so called mHealth applications, can be useful to support older persons with cognitive impairment and their informal caregivers1. However, several studies suggest that a prerequisite for older persons to start using computer-based technology is that it offers individual customization according to personal preference 2,3,4. In the ongoing Horizon 2020 project SMART4MD (Support, Monitoring And Reminder Technology for older persons with Mild Dementia), an health-oriented model app has been developed through a user-centered process involving stakeholders in six European countries and with an emphasis on customization to allow for the various needs of older persons with cognitive impairment and their informal caregivers. The aim of this study is to gain insights about the specific needs of the target group and success factors related to the user-centered design process. Method Within the frames of the SMART4MD project, an initial Feasibility study was conducted in two countries (Spain and Sweden) simultaneously, in which in total nineteen persons with cognitive impairment aged 66-93, and their respective informal caregivers, performed a taskbased usability test of the SMART4MD model app individually in a clinical setting, followed by a four-week testing of the app in their home environment. Finally, a usability evaluation was done through individual structured interviews. Results & Discussion The result indicates that less exposure to similar technology affects both ability and self-esteem when confronted with the model app, and that evaluating usability with the target group using standard forms within usability testing requires pre-cautions. © 2018 International Society for Gerontechnology.

Place, publisher, year, edition, pages
International Society for Gerontechnology, 2018
Keywords
Cognitive impairment, Innovation opportunities in gerontechnology, Usability tests
National Category
Geriatrics
Identifiers
urn:nbn:se:bth-16135 (URN)10.4017/gt.2018.17.s.079.00 (DOI)2-s2.0-85045400294 (Scopus ID)
Available from: 2018-04-26 Created: 2018-04-26 Last updated: 2018-04-27Bibliographically approved
McElhaney, J., Lal, H., Cunningham, A., Levin, M., Chlibek, R., Diez-Domingo, J., . . . Hain, J. (2018). Efficacy, Immunogenicity and Safety of adjuvanted Herpes Zoster-Virus Subunit Vaccine Candidates in Adults from 60 Years and older: Results from the Efficacy Studies ZOE-50 and ZOE-70. Der Internist, 59, S64-S65
Open this publication in new window or tab >>Efficacy, Immunogenicity and Safety of adjuvanted Herpes Zoster-Virus Subunit Vaccine Candidates in Adults from 60 Years and older: Results from the Efficacy Studies ZOE-50 and ZOE-70
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2018 (English)In: Der Internist, ISSN 0020-9554, E-ISSN 1432-1289, Vol. 59, p. S64-S65Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
SPRINGER, 2018
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:bth-16918 (URN)000439917500146 ()
Available from: 2018-08-21 Created: 2018-08-21 Last updated: 2018-08-21Bibliographically approved
Weiber, I., Tengland, P. A., Sanmartin Berglund, J. & Eklund, M. (2018). Everyday life when growing up with a mother with an intellectual or developmental disability: Four retrospective life-stories. Scandinavian Journal of Occupational Therapy
Open this publication in new window or tab >>Everyday life when growing up with a mother with an intellectual or developmental disability: Four retrospective life-stories
2018 (English)In: Scandinavian Journal of Occupational Therapy, ISSN 1103-8128, E-ISSN 1651-2014Article in journal (Refereed) Epub ahead of print
Abstract [en]

Background: The voices of those who have grown up in a family with maternal intellectual or developmental disability (IDD) are valuable for gaining an understanding of their situation, which is essential in order to be able to support these families and avoid potentially detrimental situations. Aim: The study aim was to describe the experience of having grown up in a family where the mother has an IDD, with a focus on everyday life and perceived health consequences in adult life. Method: A qualitative method with retrospective narrative interviews and narrative content analysis was chosen. In-depth interviews were performed with four women who had experiences of a childhood with maternal IDD. Findings: Four themes emerged: Living under adverse circumstances; Dealing with one’s everyday life situation; Receiving insufficient support and wishing for more; and The echo from childhood into adult life. The findings revealed a distressing childhood, characterized by neglect, abuse, anxiety, and overburdening responsibilities, and also endeavors to keep the family situation a secret, while at the same time wanting the adult world to react. Discussion: The findings can hopefully stimulate occupational therapists and other professionals to more effectively identify the situation of these children and provide support to prevent adverse future health conditions and poor well-being. © 2019, © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Place, publisher, year, edition, pages
Taylor and Francis Ltd, 2018
Keywords
activity, Childhood experiences, developmental disability, intellectual disability, maternal, qualitative interviews, support
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:bth-17593 (URN)10.1080/11038128.2018.1554087 (DOI)2-s2.0-85060351074 (Scopus ID)
Note

open access

Available from: 2019-02-11 Created: 2019-02-11 Last updated: 2019-02-11Bibliographically approved
Tell, J., Olander, E., Anderberg, P. & Sanmartin Berglund, J. (2018). Implementation of a web-based national child health-care programme in a local context: A complex facilitator role. Paper presented at 8th Nordic Health Promotion Research Conferences (NHPRC) on 20 Years of Health Promotion Research in the Nordic Countries - Health, Wellbeing and Physical Activity, Jyvaskyla, FINLAND, JUN 20-22, 2016. Scandinavian Journal of Public Health, 46(20_suppl), 80-86, Article ID suppl. 20.
Open this publication in new window or tab >>Implementation of a web-based national child health-care programme in a local context: A complex facilitator role
2018 (English)In: Scandinavian Journal of Public Health, ISSN 1403-4948, E-ISSN 1651-1905, Vol. 46, no 20_suppl, p. 80-86, article id suppl. 20Article in journal (Refereed) Published
Abstract [en]

Aim: The aim of this study was to investigate child health-care coordinators’ experiences of being a facilitator for the implementation of a new national child health-care programme in the form of a web-based national guide. Methods: The study was based on eight remote, online focus groups, using Skype for Business. A qualitative content analysis was performed. Results: The analysis generated three categories: adapt to a local context, transition challenges and led by strong incentives. There were eight subcategories. In the latent analysis, the theme ‘Being a facilitator: a complex role’ was formed to express the child health-care coordinators’ experiences. Conclusions: Facilitating a national guideline or decision support in a local context is a complex task that requires an advocating and mediating role. For successful implementation, guidelines and decision support, such as a web-based guide and the new child health-care programme, must match professional consensus and needs and be seen as relevant by all. Participation in the development and a strong bottom-up approach was important, making the web-based guide and the programme relevant to whom it is intended to serve, and for successful implementation. The study contributes valuable knowledge when planning to implement a national web-based decision support and policy programme in a local health-care context. © 2018, © Author(s) 2018.

Place, publisher, year, edition, pages
SAGE Publications Ltd, 2018
Keywords
Child health care, decision support, facilitators, guidelines, ICT, implementation, child, human, infant, Internet, newborn, organization and management, preschool child, professional standard, psychology, public health, Sweden, Child Health Services, Child, Preschool, Humans, Infant, Newborn, National Health Programs, Professional Role
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:bth-16085 (URN)10.1177/1403494817744119 (DOI)000428758300012 ()2-s2.0-85044172782 (Scopus ID)
Conference
8th Nordic Health Promotion Research Conferences (NHPRC) on 20 Years of Health Promotion Research in the Nordic Countries - Health, Wellbeing and Physical Activity, Jyvaskyla, FINLAND, JUN 20-22, 2016
Available from: 2018-04-06 Created: 2018-04-06 Last updated: 2019-01-11Bibliographically approved
Nilsson, H., Sanmartin Berglund, J. & Renvert, S. (2018). Longitudinal evaluation of periodontitis and development of cognitive decline among older adults. Journal of Clinical Periodontology, 45(10), 1142-1149
Open this publication in new window or tab >>Longitudinal evaluation of periodontitis and development of cognitive decline among older adults
2018 (English)In: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 45, no 10, p. 1142-1149Article in journal (Refereed) Published
Abstract [en]

Aim: To determine whether having periodontitis is associated with cognitive decline among older adults. Material and Methods: A prospective population study of older adults, Swedish National Study on Ageing and Care, (SNAC) provided repeated registrations of cognitive functions. Cognitive decline was defined as ≥3-points deterioration from a predetermined level at baseline, using the Mini-Mental State Examination (MMSE). Between 2001 and 2003, 715 individuals had a medical as well as a clinical and radiographic dental examination. The individuals were re-examined after 6 years. Periodontitis was defined as ≥4 mm bone loss at ≥30% of tooth sites. Social variables were captured from questionnaires. Results: The multivariate logistic regression analysis demonstrated a statistically significant association between prevalence of periodontitis and cognitive decline after adjustments of confounding factors of importance. Conclusions: A history of periodontitis may be of importance for cognitive functions among older adults. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

Place, publisher, year, edition, pages
Blackwell Munksgaard, 2018
Keywords
epidemiology, inflammation, neurocognitive disorders, older adults, periodontal diseases
National Category
Dentistry
Identifiers
urn:nbn:se:bth-17054 (URN)10.1111/jcpe.12992 (DOI)000447643700001 ()2-s2.0-85053205322 (Scopus ID)
Available from: 2018-09-27 Created: 2018-09-27 Last updated: 2018-11-01Bibliographically approved
Eivazzadeh, S., Sanmartin Berglund, J., Larsson, T., Fiedler, M. & Anderberg, P. (2018). Most Influential Qualities in Creating Satisfaction Among the Users of Health Information Systems: A Study in Seven EU Countries. JMIR Medical Informatics, 6(4), 3-21
Open this publication in new window or tab >>Most Influential Qualities in Creating Satisfaction Among the Users of Health Information Systems: A Study in Seven EU Countries
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2018 (English)In: JMIR Medical Informatics, Vol. 6, no 4, p. 3-21Article in journal (Refereed) Published
Abstract [en]

Background:

Several models suggest how the qualities of a product or service influence user satisfaction. Models, such as the Customer Satisfaction Index (CSI), Technology Acceptance Model (TAM), and Delone and McLean Information Systems Success (D&M IS), demonstrate those relations and have been used in the context of health information systems.

Objective:

We want to investigate which qualities foster greater satisfaction among patient and professional users. In addition, we are interested in knowing to what extent improvement in those qualities can explain user satisfaction and if this makes user satisfaction a proxy indicator of those qualities.

Methods:

The Unified eValuation using ONtology (UVON) method was utilised to construct an ontology of the required qualities for seven e-health applications being developed in the FI-STAR project, a European Union (EU) project in e-health. The e-health applications were deployed across seven EU countries. The ontology included and unified the required qualities of those systems together with the aspects suggested by the Model for ASsessment of Telemedicine applications (MAST) evaluation framework. Two similar questionnaires, for 87 patient users and 31 health professional users, were elicited from the ontology. In the questionnaires, user was asked if the system has improved the specified qualities and if the user was satisfied with the system. The results were analysed using Kendall correlation coefficients matrices, incorporating the quality and satisfaction aspects. For the next step, two Partial Least Squares Structural Equation Modelling (PLS-SEM) path models were developed using the quality and satisfaction measure variables and the latent construct variables that were suggested by the UVON method.

Results:

Most of the quality aspects grouped by the UVON method are highly correlated. Strong correlations in each group suggest that the grouped qualities can be measures which reflect a latent quality construct. The PLS-SEM path analysis for the patients reveals that the effectiveness, safety, and efficiency of treatment provided by the system are the most influential qualities in achieving and predicting user satisfaction. For the professional users, effectiveness and affordability are the most influential. The parameters of the PLS-SEM that are calculated allow for the measurement of a user satisfaction index similar to CSI for similar health information systems.

Conclusions:

For both patients and professionals, the effectiveness of systems highly contributes to their satisfaction. Patients care about improvements in safety and efficiency, while professionals care about improvements in the affordability of treatments with health information systems. User satisfaction is reflected more in the users' evaluation of system output and fulfilment of expectations, but slightly less in how far the system is from ideal. Investigating satisfaction scores can be a simple, fast way to infer if the system has improved the abovementioned qualities in treatment and care.

Place, publisher, year, edition, pages
JMIR Publications, 2018
Keywords
Health Information Systems, Telemedicine, Evaluation Studies as Topic, Consumer Behavior, Treatment Outcome, Safety, Efficiency, Health Care Costs, Ontology Engineering, Equation Models
National Category
Other Health Sciences
Identifiers
urn:nbn:se:bth-16998 (URN)10.2196/11252 (DOI)000454162600001 ()
Projects
MD3S
Note

Open access

Available from: 2018-09-13 Created: 2018-09-13 Last updated: 2019-01-10Bibliographically approved
Nilsson, H., Sanmartin Berglund, J. & Renvert, S. (2018). Periodontitis, tooth loss and cognitive functions among older adults. Clinical Oral Investigations, 22(5), 2103-2109
Open this publication in new window or tab >>Periodontitis, tooth loss and cognitive functions among older adults
2018 (English)In: Clinical Oral Investigations, ISSN 1432-6981, E-ISSN 1436-3771, Vol. 22, no 5, p. 2103-2109Article in journal (Refereed) Published
Abstract [en]

Objective: This study aims to evaluate the potential association between periodontitis, the number of teeth and cognitive functions in a cohort of older adults in Sweden. Material and methods: In total, 775 individuals from 60 to 99 years of age were selected for the study. A clinical and radiographic examination was performed. The number of teeth and prevalence of periodontal pockets and bone loss was calculated and categorised. Cognitive functions were assessed using the Mini-Mental State Examination (MMSE) and clock test. The education level was obtained from a questionnaire. Data were analysed using chi-square tests and multivariate logistic regression. Results: Age and gender were associated with the prevalence of bone loss. Age and education were associated with lower number of teeth. Gender was also associated with the presence of pockets. The multivariate logistic regression analysis demonstrated a statistically significant association between prevalence of bone loss, the number of teeth and the outcome on MMSE test. This association remained even after adjustment for age, education and gender. Tooth loss was also associated with lower outcome on clock test. Presence of periodontal pockets ≥ 5 mm was not associated with cognitive test outcome. Conclusions: A history of periodontitis and tooth loss may be of importance for cognitive functions among older adults. Clinical relevance: Diseases with and inflammatory profile may have an impact on cognitive decline. © 2017 Springer-Verlag GmbH Germany, part of Springer Nature

Place, publisher, year, edition, pages
Springer Verlag, 2018
Keywords
Dementia, Epidemiology, Mild cognitive impairment, Periodontal diseases and tooth loss
National Category
Dentistry
Identifiers
urn:nbn:se:bth-15714 (URN)10.1007/s00784-017-2307-8 (DOI)000431880700023 ()2-s2.0-85038611040 (Scopus ID)
Available from: 2018-01-04 Created: 2018-01-04 Last updated: 2018-05-24Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0003-4312-2246

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