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Prevalence of Atrial Fibrillation and Long-Term Survival of Older Adults; Findings from the SNAC Study
Blekinge Institute of Technology, Faculty of Engineering, Department of Health.ORCID iD: 0000-0003-3166-0274
Blekinge Institute of Technology, Faculty of Engineering, Department of Health.ORCID iD: 0000-0003-4312-2246
Stockholm University.
Karolinska Institutet.
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2024 (English)In: Gerontology and geriatric medicine, E-ISSN 2333-7214, Vol. 10Article in journal (Refereed) Published
Abstract [en]

Objective: This study examined the prevalence and long-term survival of atrial fibrillation (AF) in the older population.

Methods: Data was recruited from the longitudinal SNAC study from baseline (2001-2004) for up to 10 years.

Results: The population comprised 6,904 persons (59% women) (mean age 73.9 years). The prevalence of AF was 4.9% and increased with age. The hazard ratio (HR) for death in those with AF at baseline was 1.29 during the 10-year observation period. Cox regression analysis in persons with AF (n = 341) showed that men had a higher HR for death (1.57). CHA2DS2-VASc scores were significantly associated with death within 10 years (HR 1.29/score). Any form of anticoagulant use was reported in 146 (42.8%) and was significantly associated with survival (p = .031).

Conclusions: The prevalence of AF in the general population was almost 5%, and it shortened life expectancy by nearly 2.4 years over a 10-year period. Despite the proven efficacy of OAC therapies, our results demonstrate that AF continues to be associated with increased mortality, especially among men, and that many older people are at high risk of developing a stroke because they do not receive appropriate anticoagulant therapy. These results emphasize the need for improved preventive and therapeutic modalities.

Place, publisher, year, edition, pages
Sage Publications, 2024. Vol. 10
Keywords [en]
atrial fibrillation, long-term survival, older adults, prevalence, SNAC
National Category
Public Health, Global Health, Social Medicine and Epidemiology Cardiology and Cardiovascular Disease
Identifiers
URN: urn:nbn:se:bth-27264DOI: 10.1177/23337214241304887ISI: 001369413100001PubMedID: 39628548Scopus ID: 2-s2.0-85211173717OAI: oai:DiVA.org:bth-27264DiVA, id: diva2:1922256
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SNACAvailable from: 2024-12-18 Created: 2024-12-18 Last updated: 2025-02-10Bibliographically approved

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Lindberg, TereseSanmartin Berglund, JohanBohman, Doris

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