This paper focuses on information-driven engineering, where information is gathered by means of innovation for people and by the people. This case study was carried out on innovation of a manual wheelchair. Through active participation of person with disability (direct users) and their carers (indirect user), knowledge awareness of the early design was increased. Computer aided engineering tools were used for the development of virtual prototype (VP) and after further feedback from direct and indirect users design was adjusted. Additionally, Physical prototype was built to practically demonstrate the new features to users and finally the prototype was readjusted to bridge user requirement even more. This innovation process identifies additional improvement aspects and contributes beyond fundamental personal needs and increases well being.