Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
A prospective study on the incidence of Borrelia burgdorferi sensu lato infection after a tick bite in Sweden and On the Aland Islands, Finland (2008-2009)
Linkoping Univ, Dept Clin & Expt Med, Med Microbiol, S-58185 Linkoping, Sweden..
Linkoping Univ, Dept Clin & Expt Med, Infect Dis, S-58185 Linkoping, Sweden.;Linkoping Univ, Dept Clin & Expt Med, Clin Immunol, S-58185 Linkoping, Sweden..
Linkoping Univ, Dept Clin & Expt Med, Med Microbiol, S-58185 Linkoping, Sweden..
Linkoping Univ, Dept Infect Dis, S-58185 Linkoping, Sweden.;Linkoping Univ, Dept Clin & Expt Med, S-58185 Linkoping, Sweden..
Visa övriga samt affilieringar
2016 (Engelska)Ingår i: Ticks and Tick-borne Diseases, ISSN 1877-959X, E-ISSN 1877-9603, Vol. 7, nr 1, s. 71-79Artikel i tidskrift (Refereegranskat) Published
Resurstyp
Text
Abstract [en]

Lyme borreliosis (LB) is a common and increasing tick-borne disease in Europe. The risk of acquiring a Borrelia infection after a tick bite is not fully known. Therefore, we investigated the incidence of Borrelia infection after a bite by a Borrelia-infected tick and if the Borrelia load and/or the duration of tick-feeding influenced the risk of infection. During 2008-2009, ticks and blood samples were collected from 1546 tick-bitten persons from Sweden and the Aland Islands, Finland. Follow-up blood samples were taken 3 months after the tick bite. The duration of tick feeding was microscopically estimated and Borrelia was detected and quantified in ticks by real-time PCR. Anti-Borrelia antibodies were detected in sera using ELISA tests and immunoblot. Five percent (78/1546) of the study participants developed Borrelia infection (LB diagnosis and/or seroconversion) after a tick bite (45% bitten by Borrelia-infected ticks and 55% bitten by uninfected ticks). Of these, 33 developed LB (whereof 9 also seroconverted) while 45 participants seroconverted only. Experience of non-specific symptoms was more frequently reported by Borrelia-infected participants compared to uninfected participants. All who seroconverted removed "their" ticks significantly later than those who did not. The Borrelia load in the ticks did not explain the risk of seroconversion. Regional and sex differences in the Borrelia seroprevalence were found. The risk of developing a Borrelia infection after a bite by a Borrelia-infected tick is small but increases with the duration of tick feeding. (C) 2015 Elsevier GmbH. All rights reserved.

Ort, förlag, år, upplaga, sidor
2016. Vol. 7, nr 1, s. 71-79
Nyckelord [en]
Borrelia burgdorferi sensu lato, Tick bite, Lyme borreliosis, Asymptomatic infection, Bacterial load, Tick-feeding
Nationell ämneskategori
Infektionsmedicin
Identifikatorer
URN: urn:nbn:se:bth-11537DOI: 10.1016/j.ttbdis.2015.08.009ISI: 000366953400012PubMedID: 26341726OAI: oai:DiVA.org:bth-11537DiVA, id: diva2:899802
Tillgänglig från: 2016-02-02 Skapad: 2016-02-02 Senast uppdaterad: 2017-11-30Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Berglund, Johan

Sök vidare i DiVA

Av författaren/redaktören
Berglund, Johan
Av organisationen
Institutionen för hälsa
I samma tidskrift
Ticks and Tick-borne Diseases
Infektionsmedicin

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 176 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf