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Surgical treatment of peri-implantitis lesions with or without the use of a bone substitute: a randomized clinical trial
Blekinge Institute of Technology, Faculty of Engineering, Department of Health.
Public Dental Health Service, Department of Periodontology, Karlskrona, SWE.
Hogskolan Kristianstad, SWE.
2018 (English)In: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 45, no 10, p. 1266-1274Article in journal (Refereed) Published
Abstract [en]

Aim: To assess whether the treatment outcome differed between surgical debridement, with or without a bone substitute. Materials and Methods: Forty-one adults with three- or four-wall peri-implant bone defects were enrolled in a 1-year RCT. Surgical debridement (control group), or in combination with a bone substitute (Endobon®) (test group) was performed. Results: Radiographic evidence of defect fill (primary outcome) was only significant in the test group (P = 0.004). At year 1, no bleeding on probing (BOP) in the control and test groups were 7/20 (35%) and 10/21 (47.6%), respectively (χ2= 0.67, P = 0.41). Plaque scores did not differ by study group at baseline (P = 0.31), or at year 1 (P = 0.08). Mid-buccal soft tissue recession changes did not differ by groups (P = 0.76). Successful treatment outcome (defect fill ≥1.0 mm, PPD values at implant ≤5 mm, no BOP, and no suppuration was identified in 1/20 (5.0%) control, and 9/21 (42.9%) test individuals (F = 7, 9, P < 0.01). Number needed to treat analysis identified an absolute risk reduction of 32.8% in benefit of the test procedure. (F = 7, 9, P < 0.01). Conclusions: Successful treatment outcome using a bone substitute was more predictable when a composite therapeutic endpoint was considered. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

Place, publisher, year, edition, pages
Blackwell Munksgaard , 2018. Vol. 45, no 10, p. 1266-1274
Keywords [en]
bone grafting, peri-implantitis, radiographs, surgical treatment
National Category
Dentistry
Identifiers
URN: urn:nbn:se:bth-17055DOI: 10.1111/jcpe.12986ISI: 000447643700012Scopus ID: 2-s2.0-85053244614OAI: oai:DiVA.org:bth-17055DiVA, id: diva2:1251465
Available from: 2018-09-27 Created: 2018-09-27 Last updated: 2018-11-01Bibliographically approved

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Renvert, Stefan

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