Experimental characterization of the mechanical properties in a thin injection moulded Low-Density Polyethylene (LDPE) plate is per- formed in this work. Anisotropy in LDPE at different material orientations is measured from the Digital Image Correlation (DIC) observation of the specimens during uniaxial tensile test. From the test response and observation from DIC, the studied material is found to be significantly anisotropic. Finite Element simulation (FE-simulation) of in-plane anisotropy of material is carried in AbaqusTM R2020 using available models like Hill48 and Barlat2004. When necessary the simulation plastic potentials for these models are optimized against experimental yield stress ratio (R) and anisotropic ratio (r). To express the nonlinear mechanical behavior, a suitable hardening extrapolation model, namely Swift/Hockett-Sherby is selected from several extrapolation models based on experimental data. To validate the experimental methods, simulation methods and material characterization process, finite element simulation results such as force displacement, strain distribution and different anisotropic related properties are compared with the experimental data. Finally, advantages and disadvantages of different simulation models are discussed.