Recent developments using extended reality (XR) technologies have allowed for increased use in healthcare in the last few years. This review paper explores how XR applications are utilized in home-based nursing education, in particular, to identify future challenges and opportunities. The systematic literature review evaluates relevant extracted papers based on publication information, XR technology used for education purposes, target users, and study design and evaluation, including sample size. The results show potential for using XR technologies in home-based nursing education. In particular, Virtual Reality (VR) has become quite popular and the most used to date. However, Augmented Reality (AR) has also emerged as an alternative for the future.