Institutions of higher educations (IHE), particularly universities, have a significant role to play in the global transformation to socio-ecological sustainability. This study focuses on the strategic planning efforts of one university, the University of Canterbury in Christchurch, New Zealand where The Natural Step Framework (TNSF) is being used to develop a pan-University Sustainability Plan. Drawing upon the triple helix model of university-government-industry interactions for knowledge creation, and integrating principles of education for sustainable development into strategic organizational learning and change processes within higher education, this study suggests that advocates for sustainability within IHE can use the TNSF to assess institutional barriers and communicate specific opportunities in order to institutionalize strategic sustainable development and promote socio-ecological innovation.