The area of eHealth has been increased in the recent age but also facing a lot of challenges. In relation to these, there exists a lack of interoperability among different healthcare organizations in the way of providing care services to the healthcare professionals and the patients. Interoperability among the healthcare organizations is appreciated not only by the academia but also by the policy-makers and other related personnel. Today, implementation of interoperability has become an intricate job than expectations. Interoperability is resisted by different barriers but potentially can give several benefits to all stakeholders and ultimately should be focused. The study is conducted for investigation of challenges and benefits of interoperability among healthcare organizations in the Blekinge County. In the first phase, after having a comprehensive review of literature, the challenges and benefits for the implementation of interoperability among Swedish healthcare organizations are identified. Depending on the findings, interviews were conducted with the eHealth professionals of the Blekinge County to clearly understand about the strategies and plans regarding the interoperability among the healthcare organizations in the Blekinge County. After performing a thorough analysis, questionnaire were conducted with the Medical IT administrators and with other related personnel to know about their opinions about the problem. The authors find after analyzing the results of the study that focus on resolving issues like standards adaptation, accessibility, integration, privacy and proper ICT infrastructure could provide interoperable environment among municipality healthcare centers and hospitals in the Blekinge County and other areas in the Sweden.