Extending previous research by Bowling and Burns (2010), a comparison of work personality to general personality indicate that work personality has a stronger relationship with job satisfaction (work-criteria) than does general personality, and, contrary to the above study, general personality has a stronger relationship with life satisfaction (general criteria) than does work personality. Work personality is defined as the personality in the context of work, by promoting the use of a frame-of-reference. Some of these work personality-job satisfaction, and general personality-life satisfaction relationships further predict incremental validity in their corresponding criteria after work, or general, personality is controlled for. The study includes self-reported data from 90 Swedish employees from three randomly selected municipalities and occupational areas, and the outcomes rely on correlational and regression analyses. The results partly support the use of a frame-of-reference in order to enhance the predictive strength of personality measures in a work setting. Implications are discussed.