In the light of challenges the lack of interoperability in systems and services has long been recognized as one of the major challenge to the wider implementation of the eHealth applications. The opportunities and positive benefits of achieving interoperability are eventually considerable, whereas various barriers and challenges act as impediments. The purpose of this study was to investigate the interoperability among different health care organizations. The knowledge of this study would be supportive to health care organizations to understand the interoperability problems in health care organizations. In the first phase of literature review interoperability challenges in Sweden and other EU countries were identified. On the basis of findings interviews were conducted to know the strategies and planning about interoperability in health care organizations. After analysis of interviews, questionnaires were conducted to know the opinions of different medical IT administrator and health professionals. The authors find after the analysis of interviews and questionnaire that adopting eHealth standard, same system, insuring the security of patient’s health record information and same medical language could be implemented in Sweden and other EU countries health organizations.