IT-Business alignment is an imperative process in the success of any business to use the competitive advantage of the information technology. In this work, influence of contextual information on IT-Business alignment has been studied. For this purpose, a conceptual model has been proposed which considers the IT-Business alignment model and national culture as contextual information. For alignment model, strategic alignment maturity model (SAMM) by Luftmann has been used while Hofstede’s model has been followed for the analysis of national culture. Conceptual model considers the 6 maturity assessment elements and analyzes them in the perspective of 4 national cultural factors. Survey methodology has been employed with questionnaire technique to compute the SAMM elements. National cultural scores have been obtained from the empirical study of Hofstede. Empirical results of SAMM elements and cultural factors have been used to support the analysis of the conceptual model.