Cluster of Bacteria Associated with Peri-Implantitis
2014 (English)In: Clinical Implant Dentistry and Related Research, ISSN 1523-0899, E-ISSN 1708-8208, Vol. 16, no 6, 783-893 p.Article in journal (Refereed) Published
Information on the microbiota in peri-implantitis is limited. We hypothesized that neither gender nor a history of periodontitis/smoking or the microbiota at implants differ by implant status. Materials and Methods: Baseline microbiological samples collected at one implant in each of 166 participants with peri-implantitis and from 47 individuals with a healthy implant were collected and analyzed by DNA-DNA checkerboard hybridization (78 species). Clinical and radiographic data defined implant status. Results: Nineteen bacterial species were found at higher counts from implants with peri-implantitis including Aggregatibacter actinomycetemcomitans, Campylobacter gracilis, Campylobacter rectus, Campylobacter showae, Helicobacter pylori, Haemophilus influenzae, Porphyromonas gingivalis, Staphylococcus aureus, Staphylococcus anaerobius, Streptococcus intermedius, Streptococcus mitis, Tannerella forsythia, Treponema denticola, and Treponema socranskii (p<.001). Receiver operating characteristic curve analysis identified T. forsythia, P. gingivalis, T. socranskii, Staph. aureus, Staph. anaerobius, Strep. intermedius, and Strep. mitis in peri-implantitis comprising 30% of the total microbiota. When adjusted for gender (not significant [NS]), smoking status (NS), older age (p=.003), periodontitis history (p<.01), and T. forsythia (likelihood ratio 3.6, 95% confidence interval 1.4, 9.1, p=.007) were associated with peri-implantitis. Conclusion: A cluster of bacteria including T. forsythia and Staph. aureus are associated with peri-implantitis.
Place, publisher, year, edition, pages
Wiley , 2014. Vol. 16, no 6, 783-893 p.
DNA analysis, Microbiota, Peri-implantitis
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:bth-6347DOI: 10.1111/cid.12052ISI: 000347039400001Local ID: oai:bth.se:forskinfo0A741899A68556E7C1257B950023DAEDOAI: oai:DiVA.org:bth-6347DiVA: diva2:833844