Today it is realized by industry that automation of software development leads to increased productivity, maintainability and higher quality. Model-Driven Development (MDD) aims to replace manual software development methods by automated methods using Domain-Specific Languages (DSLs) to express domain concepts effectively. Main actors in software industry, Microsoft and IBM have recognized the need to provide technologies and tools to allow building DSLs to support MDD. On the one hand, Microsoft is building DSL Tools integrated in Visual Studio 2005; on the other hand IBM is contributing to the development of Eclipse Modeling Frameworks (EMF/GEF/GMF), both tools aim to make development and deployment of DSLs easier. Software practitioners seek for guidelines regarding how to adopt these tools. In this thesis, the author presents the current state-of-the-art in MDD standards and Domain-Specific Modeling (DSM). Furthermore, the author presents current state-of-the-tools for DSM and performs a comparison of Microsoft DSL Tools and Eclipse EMF/GEF/GMF Frameworks based on a set of evaluation criteria. For the purpose of comparison the author developed two DSL designers (one by using each DSM tool). Based on the experiences gained in development of these DSL designers, the author prepared guidelines regarding how to adopt these tools to existing development environments as well as their advantages and drawbacks.